Efficacy of various tranexamic acid administration techniques to reduce blood loss in TKA .
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Reduced blood loss after intra-articular tranexamic acid injection during total knee arthroplasty: a meta-analysis of the literature
Knee Surg Sports Traumatol Arthrosc. 2014 Dec;22(12):3181-90.6 randomized controlled trials were included in this meta-analysis examining the efficacy of tranexamic acid (TXA) through intra-articular administration when compared to placebo, no TXA administration, or intravenous TXA administration. Efficacy was evaluated through blood loss, transfusion rate, and hemoglobin and hematocrit drop, and safety was assessed through the incidence of venous thromboembolic (VTE) complications. Results demonstrated topical TXA significantly reduced blood loss (total and postoperative drainage), mitigated hemoglobin drop, and reduced the rate of transfusion when compared to placebo/control. The risk of deep vein thrombosis was not revealed to be significantly increased with the use of topical TXA when compared to placebo/control.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidencecontent for as little as $1.99 per week.
Already have an account? Log in
0 of 4 monthly FREE articles unlocked
