Efficacy of Platelet-Rich Plasma vs Placebo for the Treatment of Greater Trochanteric Pain Syndrome .
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Efficacy of Platelet-Rich Plasma Versus Placebo for the Treatment of Greater Trochanteric Pain Syndrome: A Double-Blinded Randomized Controlled Trial.
J Bone Joint Surg Am . 2025 Mar 5;107(5):444-451.Seventy-nine patients with greater trochanteric pain syndrome unresponsive to conservative treatment were randomized to receive a single ultrasound-guided injection of leukocyte-rich platelet-rich plasma (n=39) or saline placebo (n=40). The primary outcome of interest was the iHOT-12 score. Secondary outcomes included VAS for pain, EQ-5D index, EQ-5D VAS, and mHHS scores. Outcomes were assessed at 3, 6, and 12 months. Overall, the results of the study revealed no significant differences in any outcome measures between the PRP and placebo groups at any follow-up point. This suggests that LR-PRP does not provide added clinical benefit over placebo in treating refractory GTPS.
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