Cardiovascular events in patients undergoing hip fracture surgery treated with remote ischaemic preconditioning: 1-year follow-up of a randomised clinical trial.

研究概要

Six hundred and forty-eight patients undergoing a hip fracture surgery were randomized to receive remote ischemic preconditioning (n=316) or no treatment (n=309); this was a 1 year follow up study. The primary outcome of interest was the incidence of major adverse cardiovascular events. Secondary outcomes of interest included myocardial infarction, heart failure, stroke, non-fatal cardiac arrest, coronary revascularization procedure, clinically important arrhythmia, peripheral arterial thrombosis, cardiovascular rehospitalization, and all-cause mortality. Outcomes were assessed 1 year post-operation. No significant differences in all outcomes were observed between the two groups, with the exception of the rate of myocardial infarction which was significantly lower in the remote ischemic preconditioning group.