Effect of Platelet-Rich Plasma Injection for the Treatment of Achilles Tendinopathy .
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Effect of Platelet-Rich Plasma Injection on the Treatment of Achilles Tendinopathy: A Systematic Review and Meta-analysis.
Orthop J Sports Med . 2024 Nov 27;12(11):23259671241296508.Six studies involving 422 patients with chronic midportion Achilles tendinopathy were included in this systematic review and meta-analysis comparing PRP injections with nonoperative treatments. Pooled outcomes included VISA-A scores and maximal Achilles tendon (AT) thickness across three time points (3, 6, and 12 months). No significant differences were observed in functional outcomes (VISA-A score) or tendon thickness between PRP and control groups at any time point (e.g., short-term VISA-A, p = 0.29; intermediate-term AT thickness, p = 0.20). This review suggests that current evidence does not support PRP injection as a superior treatment for Achilles tendinopathy and highlights the need for better-designed trials.
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