Nine studies containing a total of 369 patients with knee injury were included in this meta-analysis comparing low load blood flow restriction (BFR) training (n=179) to low load non-BFR resistance training (n=94) and high load non-BFR resistance training (n=96). The pooled outcomes of interest included knee muscle strength and pain scores. Meta-analysis results revealed significantly favourable pooled knee muscle strength in the BFR group compared to the low load group (p<0.0001); no significant differences in pooled knee muscle strength were observed between the BFR group and high load group (p=0.66). Moreover, pooled pain scores were significantly in favour of the BFR group compared to the high load group (p=0.04), particularly in patients with knee pain (p<0.001). No significant difference in pooled knee pain scores were observed between the BFR group and low load group (p=0.58).