Study Summary

70 patients undergoing hip fracture surgery were randomized to receive either fascia iliaca compartment block with liposomal bupivacaine or ropivacaine. Three participants in the ropivacaine group withdrew during follow-up, resulting in 35 analyzed in the liposomal bupivacaine group and 32 analyzed in the ropivacaine group. The outcomes were postoperative quality of recovery measured using the Quality of Recovery-15 (QoR-15) score at 72 hours after surgery, the highest Numerical Rating Scale (NRS) pain score during activity at multiple postoperative intervals, opioid consumption within 72 hours, recovery time for muscle strength grades II and III, time to first postoperative mobilization, length of hospital stay, postoperative adverse reactions, and patient satisfaction with analgesia. Outcomes were assessed during the first 72 hours following surgery. Overall, the results of the study revealed that patients receiving liposomal bupivacaine demonstrated improved postoperative recovery quality, lower opioid consumption, and earlier mobilization compared with those receiving ropivacaine. These findings suggest that liposomal bupivacaine may enhance early postoperative recovery after hip fracture surgery.