Early Weightbearing vs. Nonweightbearing in Operative Ankle Fractures .
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Early Weightbearing Versus Nonweightbearing After Operative Treatment of an Ankle Fracture: A Multicenter, Noninferiority, Randomized Controlled Trial.
Am J Sports Med. 2021 Aug;49(10): 2689-2696.One hundred and ninety four patients with operative ankle fractures were randomized to undergo early weightbearing (EWB) at 2 weeks postoperatively (n=95) or nonweightbearing (NWB) (n=99) until 6 weeks postoperatively. This was a noninferiority trial design. The primary outcome of interest was the mean difference in the Olerud-Molander ankle score (OMAS) between the two groups at 12 month follow-up. Additional outcomes of interest included time to full weightbearing, time to return to preinjury activities and patient satisfaction. The EWB group demonstrated a noninferior mean difference in the OMAS score when compared to the NWB group. There was no difference in the proportion of patients who were satisfied at 12 month follow-up. The EWB demonstrated shorter time to full weightbearing and return to preinjury activities than the NWB group (p<0.001). No differences in adverse events were noted.
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