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Osteoarthritis

Dietary Hyaluronan, Glucosamine, and Chondroitin Mix for Moderate Pain from Knee Osteoarthritis

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OSTEOARTHRITIS

Dietary Hyaluronan, Glucosamine, and Chondroitin Mix for Moderate Pain from Knee Osteoarthritis .

This report has been verified by one or more authors of the original publication.

Liquid combination of hyaluronan, glucosamine, and chondroitin as a dietary supplement for knee osteoarthritis patients with moderate knee pain: A randomized controlled study

Medicine (Baltimore). 2021 Oct 8;100(40): e27405.

Contributing Authors

SJ Wang YH Wang LC Huang

Ninety-seven patients reporting moderate pain from knee osteoarthritis were randomized to receive 8 weeks of daily dietary supplementation with a oral mixture of hyaluronic acid, glucosamine, and chondroitin (n=47) or an oral placebo (n=50). The primary outcome of interest was the change from baseline in Knee Injury and Osteoarthritis Outcomes Scores (KOOS). Secondary outcomes of interest included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Short Form 36 (SF-36) quality of life questionnaire, and the Chinese version of Pittsburgh Sleep Quality Index (CPSQI). Outcomes were assessed after completion of the intervention period. No significant differences in all outcomes were observed between the two groups.

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