Hypertonic dextrose versus corticosteroid local injection for the treatment of osteoarthritis in the first carpometacarpal joint: a double-blind randomized clinical trial

This report has been verified by one or more authors of the original publication.

60 patients suffering from osteoarthritis of the first carpometacarpal joint were randomly allocated to receive 3 monthly injections of dextrose or a single corticosteroid injection after 2 monthly placebo injections. The purpose of this study was to determine which treatment improves symptoms and restores function more effectively up to 6 months post-intervention. Dextrose achieved greater pain relief and function restoration than corticosteroid injections at final follow-up.