Dexamethasone-Enhanced Adductor Canal Block for Persistent Pain After ACL Reconstruction .
Dexamethasone as an additive to bupivacaine in an ultrasound-guided adductor canal block for the management of persistent pain after arthroscopic reconstruction of the anterior cruciate ligament: a randomized, double-blind study.
BMC Anesthesiol . 2025 Apr 24;25(1):208.Study Summary
Ninety patients undergoing arthroscopic ACL reconstruction were randomized to receive either a 20 ml mixture of 0.25% bupivacaine plus 8 mg dexamethasone (n=45) or 20 ml of 0.25% bupivacaine with saline (n=45) via ultrasound-guided adductor canal block. The primary outcome was the dynamic visual analog score (DVAS) at 1 month. Secondary outcomes included postoperative VAS scores at 24 hours, DVAS at 2 and 3 months, time to first analgesic request, and opioid consumption up to 3 months. Overall, the results of the study revealed that the dexamethasone group had significantly longer analgesia duration, lower opioid use, and reduced pain severity up to 3 months. These findings suggest that perineural dexamethasone is effective in reducing persistent pain and opioid reliance after ACL reconstruction.
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