Demineralized bone matrix vs. B-tricalcium phosphate graft material for ACDF .
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A Prospective Randomized Clinical Trial Comparing Bone Union Rate Following Anterior Cervical Discectomy and Fusion Using a Polyetheretherketone Cage: Hydroxyapatite/B-Tricalcium Phosphate Mixture versus Hydroxyapatite/Demineralized Bone Matrix Mixture
Asian Spine J. 2015 Feb;9(1):30-885 patients scheduled for single level anterior cervical discectomy and fusion (ACDF) were randomized to one of two graft materials. PEEK cages of one group were filled with a hydroxyapatite and demineralized bone matrix (HA/DBM) mixture, and in the other group with a hydroxyapatite and beta-tricalcium phosphate (HA/B-TCP) mixture. The purpose of this study was to test the noninferiority of the HA/DBM versus standard HA/B-TCP. Fusion rate and clinical outcomes were assessed at 3, 6, and 12 months after surgery. Results demonstrated no significant differences between groups for any outcome.
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