Steroid Injection for Osteoarthritis of the Hip A Randomized, Double-Blind, Placebo-Controlled Trial

この研究はインパクトが大きい可能性があると判断されました。 OEのAIによるハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文の影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することができ、読者は将来の診療を形成する可能性が最も高い論文に焦点を当てることができます。

研究概要

Fifty-two patients with primary hip osteoarthritis (OA) were randomized to receive either a corticosteroid or placebo injection for the relief of pain, and improvement of function and quality of life. The primary outcome of interest was pain scored on the Western Ontario and McMaster Universities Arthritis index (WOMAC). Secondary outcomes of interest included WOMAC stiffness and physical function scores, a patient's global assessment of health, Short-Form 36 (SF-36) physical component, bodily pain, physical function and social function scores, internal and external rotation, and analgesic pill count. Outcomes were assessed at 1, 2, 3, and 6 months post-treatment; however, data were lacking for 3 and 6 months post-treatment due to severe attrition in follow-up numbers. The corticosteroid group reported significantly favourable WOMAC sub-scales for pain, stiffness, and physical function scores, patient's global assessment of health scores, and SF-36 physical component, bodily pain, physical function, and social function scores compared to the placebo group. No significant differences in internal or external rotation, or analgesic pill count were observed between the two treatment groups.