Riassunto dello studio

One hundred and sixty-three postmenopausal women and men over the age of 50 with fragility fractures were randomized to receive 2 years of coordinator-based osteoporosis intervention (n=83) or standard care (n=80) for the improvement of osteoporosis treatment and fracture prevention. The primary outcome of interest was osteoporosis treatment commencement and persistence rate. Secondary outcomes of interests included the incidence of falls and fractures. Additionally, the rate of bone mineral measurement performance was recorded. Outcomes were assessed at baseline, as well as 3 months, 6 months, 1 year and 2 years follow-up. Results revealed a statistically significantly higher rate of osteoporosis treatment commencement in the coordinator-based group compared to the standard care group (85.7% vs 71.8%, p=0.04), however osteoporosis treatment persistence was similar between the two groups at the remaining time-points (p>0.05 for all). Moreover, the rate of bone mineral measurements was statistically significantly higher in the coordinator-based group at baseline and 6 months follow up (p<0.05 for both). No statistically significant differences in the incidence of falls or fractures were observed between the two groups at any time-point (p>0.05 for all), and no cases of osteonecrosis of the jaw nor atypical fracture were observed in either group.