Continuous infusion of bupivacaine following TKA does not improve morphine consumption .
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by one or more authors of the
original publication.
Continuous infusion of bupivacaine following total knee arthroplasty: a randomized control trial pilot study
J Arthroplasty. 2013 Mar;28(3):479-84. doi: 10.1016/j.arth.2012.07.016. Epub 2012 Nov 267 patients were randomized in this pilot study to evaluate the efficacy of a 48h continuous local infiltration of bupivacaine on reducing morphine consumption following total knee arthroplasty (TKA). Patients received either local infiltration of intra-articular bupivacaine (0.5% at 2 cc/h) or placebo (0.5% saline at 2 cc/h) and were assessed over the first 48 hours and at 1 year. Results revealed that there were no significant differences between both groups regarding morphine consumption, pain scores, or any of the other clinical outcome measures.
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