Comparison Of Intra-Articular Ozone And Steroid Injection In Patients With Adhesive Capsulitis .
Comparison of intra-articular ozone and steroid injection in patients with adhesive capsulitis.
Clin Rheumatol . 2025 Jun;44(6):2517-2525.Forty patients with MRI/ultrasound-confirmed adhesive capsulitis were randomized to receive intra-articular ozone (eight sessions; n=20) or a single intra-articular betamethasone injection (n=20). The primary outcome was pain (VAS). Secondary outcomes were SPADI and active/passive ROM. Outcomes were assessed at baseline, 4 weeks, and 12 weeks by a blinded assessor. Overall, the results revealed significant within-group improvements in VAS, SPADI, and ROM through 12 weeks, with no between-group differences. These findings suggest that an eight-session ozone regimen achieved improvements comparable to a single steroid injection over 12 weeks.
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