OrthoEvidence - AceReport

Previous Ace Report Swedish Massage for Improvement of Pain in Rheumatoid Arthritis Next Ace Report Periarticular Multidrug Injection versus Epidural Catheter in Total Hip Arthroplasty

Osteoarthritis

Combining Platelet-Rich Plasma With Open-Wedge High Tibial Osteotomy for Knee Osteoarthritis

Language

Download

Cite

+ Favorites

Language

Download

Cite

+ Favorites

OSTEOARTHRITIS

Combining Platelet-Rich Plasma With Open-Wedge High Tibial Osteotomy for Knee Osteoarthritis .

Intra-articular Pure Platelet-Rich Plasma Combined With Open-Wedge High Tibial Osteotomy Improves Clinical Outcomes and Minimal Joint Space Width Compared With High Tibial Osteotomy Alone in Knee Osteoarthritis: A Prospective Study

Arthroscopy. 2022 Feb;38(2): 476-485.

Contributing Authors

Q Zhang W Xu K Wu W Fu H Yang JJ Guo

Ninety-six patients with medial compartment knee osteoarthritis were randomized to receive a opening-wedge high tibial osteotomy with a platelet-rich plasma injection (PRP) (n=48) or without any additional treatment (n=48). Outcomes of interest included pain on a Visual Analog Scale (VAS), the Western Ontario and McMaster University Osteoarthritis Index, Lysholm score, minimum medial joint space width, and mechanical alignment, assessed up to 24 months post-operation. Results revealed a significantly improved minimum medial joint space width in the PRP group. Moreover, a higher proportion of patients in the PRP group exceeded the minimum clinically important difference in the first year for Lysholm and WOMAC scores; this was particularly pronounced in the first 6 months of follow-up.

Unlock the Full ACE Report

You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports

Unlock Now

Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics

Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics

Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions

Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics

Or upgrade today and gain access to all OrthoEvidence
content for as little as $1.99 per week.

0 of 4 monthly FREE articles unlocked

You've reached your limit of 4 free articles views this month