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Hand & Wrist
Collagenase injections: A non-surgical modality in treating Dupuytren's Disease
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HAND & WRIST
Collagenase injections: A non-surgical modality in treating Dupuytren's Disease .

Injectable collagenase Clostridium histolyticum: A new nonsurgical treatment for Dupuytren's disease

Journal of Hand Surgery American; 2010; 35(A); 2027-2038
Contributing Authors

D Gilpin S Coleman S Hall A Houston J Karrasch N Jones

66 patients with contractures, affecting either the metacarpophalangeal (MCP) or proximal interphalangeal (PIP) joints, were randomized to receive Xiaflex (collagenase clostridium histolyticum) or placebo local injection. The results of the 9-month long trial indicated that patients who received Xiaflex displayed significantly greater range of motion and a significantly decreased degree of joint contracture. Additionally, it was found that patients who received Xiaflex were more satisfied than those who received placebo.

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OrthoEvidence. Collagenase injections: A non-surgical modality in treating Dupuytren's Disease. ACE Report. 2013;2(2):75. Available from: https://myorthoevidence.com/AceReport/Show/collagenase-injections-a-non-surgical-modality-in-treating-dupuytren-s-disease

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