COA 2020: No Improvement in Survival Trend for Surgically Treated Appendicular Bone Metastases
Longitudinal survival trends of patients with surgically managed appendicular metastatic bone disease: A systematic review
One hundred and three studies were included for analysis whereby all studies were non-randomized. The primary aim of the study was to evaluate the long-term trend in overall survival for patients with appendicular metastatic bone disease who underwent orthopaedic surgery for treatment within the last 50 years. No significant effect of mid-point study year on 1-year, 2-year, or 3-year survival were found (p=0.83; p=0.62; p=0.60, respectively). An association was not found between tumour severity score or 1-year survival. In general, no improvement was found in the overall survival of these patients over the past 50 years.
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