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COA 2016: No efficacy in the addition of epimorph to spinal anaesthesia for pain in TKA
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COA 2016: No efficacy in the addition of epimorph to spinal anaesthesia for pain in TKA .

Evaluation of the use of Spinal Epimorph in Total Knee Arthroplasty: A Prospective Double-blinded Randomized Control Trial

41 patients scheduled to undergo total knee arthroplasty (TKA) were randomized to undergo the procedure with spinal anaesthesia with our without the addition of epimorph. The purpose of this study was to determine if the addition of epimorph to spinal anaesthesia yielded significantly greater pain control and decreased consumption of narcotics without increasing postoperative complication rates. Outcomes were assessed up one week postoperatively, and consisted of the visual analogue scale (VAS) for pain, narcotic use, Foley insertion, oxygen requirements, nausea, vomiting, and pruritus. Findings indicated higher VAS pain scores and similar narcotic consumption, as well as greater incidence of nausea and pruritus were reported in the spinal epimorph group compared to the spinal-only group.

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OrthoEvidence. COA 2016: No efficacy in the addition of epimorph to spinal anaesthesia for pain in TKA. ACE Report. 2016;5(6):55. Available from: https://myorthoevidence.com/AceReport/Show/coa-2016-no-efficacy-in-the-addition-of-epimorph-to-spinal-anaesthesia-for-pain-in-tka

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