COA 2015: Adding morphine and ketorolac to periarticular multimodal injection lowers pain .
Periarticular Multimodal Drug Injection is Better than Single Anaesthetic Drug in Controlling Pain after TKA: A Double Blinded RCT
64 patients were randomized to receive either a multimodal drug injection or a single anesthetic injection for pain reduction following total knee arthroplasty. The goal of this study was to determine a standard dosage and composition for periarticular drug injection. The results indicated that the multimodal injection that included morphine and ketorolac provided better pain management, lower opioid consumption, and a longer period before on set of opioid consumption, as compared to the single anesthetic injection.
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