The Effectiveness of Closed-Incision Negative-Pressure Therapy Versus Silver-Impregnated Dressings in Mitigating Surgical Site Complications in High-Risk Patients After Revision Knee Arthroplasty: The PROMISES Randomized Controlled Trial.

この研究はインパクトが大きい可能性があると判断されました。 OEのAIによるハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文の影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することができ、読者は将来の診療を形成する可能性が最も高い論文に焦点を当てることができます。

研究概要

Two hundred and ninety-four patients who underwent a revision total knee arthroplasty and were at high-risk of surgical site complications were randomized to receive closed-incision negative pressure therapy (n=147) or silver-impregnated antimicrobial dressing (n=147). The primary outcome of interest was 90-day occurrence of surgical site complications. Secondary outcomes of interest included 30-day and 45 day surgical site complication rates, re-admission, number of dressing changes, adverse events, and patient-reported pain, and patient-reported physical and mental health. Closed-incision negative pressure wound therapy provided significantly lower occurrence of 90-day surgical site complications. The number of dressing changes and the rate of readmission was significantly lower in the closed-incision negative pressure wound therapy group. No significant differences in patient reported pain, physical health or mental health were observed between groups at 90 days.