Fifty-five patients with chronic low back pain and mild disability were randomized into three groups: exercise alone (n=19), exercise with manual therapy (n=18), or exercise with kinesiotaping (n=18). The primary outcome was disability, measured using the Oswestry Disability Index. Secondary outcomes included pain sensitivity, kinesiophobia, catastrophizing, and self-efficacy. Outcomes were assessed at baseline and at 3, 6, and 12 weeks. Overall, all groups showed improvements in all parameters over time. The manual therapy group demonstrated the greatest improvements in disability and other measures, achieving a clinically significant reduction in disability scores earlier than other groups. These findings suggest that adding manual therapy to core stabilization exercises may provide enhanced short-term benefits.