Use of Closed Incisional Negative Pressure Wound Therapy After Revision Total Hip and Knee Arthroplasty in Patients at High Risk for Infection: A Prospective, Randomized Clinical Trial

この研究はハイインパクトの可能性があります。 OEのAI駆動型ハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文が持つ可能性の高い影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することが可能になり、読者は将来の診療を形成する可能性が最も高い論文に集中することができます。

160 patients scheduled for a total joint arthroplasty (hip/knee) were randomized to receive either a closed incision negative pressure wound therapy (ciNPWT; PREVENA) device or a standard-of-care silver-impregnated occlusive wound dressing. The primary outcome of interest was the incidence of wound complications. Secondary outcomes included the rates or re-admission and re-operation. Follow up was performed at 2 weeks, 4 weeks, and 12 weeks post-surgery. Results revealed a significantly favourable rate of wound complications in the ciNPWT group compared to the control group at 2 weeks and overall. The rate of re-operation was significantly in favour of the ciNPWT group at 12 weeks and overall compared to the control group. Two cases of infection were reported in the ciNPWT group, whilst 8 cases were reported in the control group. No differences were observed in the rate of re-admission between the two groups.