Chaperonin 10: Short term relief for rheumatoid arthritis patients .
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Therapeutic efficacy and safety of chaperonin 10 in patients with rheumatoid arthritis: a double-blind randomised trial
Lancet. 2006 Dec 2;368(9551):1964.23 patients with moderate to severe active rheumatoid arthritis were randomized to receive either 5 mg, 7.5 mg, or 10 mg of Chaperonin 10, an anti-inflammatory drug, intravenously twice weekly for 12 weeks. Disease activity score and core disease measures were assessed throughout the course of the study. By the end of the 12 week study, it was determined that improvement in rheumatoid arthritis was found in all three treatment groups with the 10 mg group having consistently better outcome scores than the 5 mg and 7.5 mg groups.
Unlock the Full ACE Report
You have access to 4 more FREE articles this month.
Click below to unlock and view this ACE Reports
Unlock Now
Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics