Bupivacaine infusion pumps non-superior to placebo for analgesia after rotator cuff repair .
The Efficacy of Continuous Bupivacaine Infiltration Following Arthroscopic Rotator Cuff Repair
Arthroscopy. 2008 Apr;24(4):397-402. Epub 2008 Jan 7.60 patients undergoing arthroscopic rotator cuff repair received a bolus injection of 35 mL of 0.25% bupivacaine with 1:200,000 epinephrine in the subacromial space at surgical closure. Afterwards, they were randomized to receive either 0.25% bupivacaine at 2 mL/hr, 0.25% bupivacaine at 5 mL/hr, or saline (placebo) at 5 mL/hr via infusion pump, in order to assess the effectiveness of infusion pumps in lowering post-operative pain. Following evaluations over a 48 hour period, no significant difference was observed among the 2-mL, 5-mL, and placebo groups. Although pain was lower in the 2 mL group, this observation was not statistically significant. Results indicated that the efficacy of infusion pumps is still unclear.
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