Polyurethane on titanium unconstrained disc arthroplasty versus anterior discectomy and fusion for the treatment of cervical disc disease: a review of level I-II randomized clinical trials including clinical outcomes

この研究はハイインパクトの可能性があります。 OEのAI駆動型ハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文が持つ可能性の高い影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することが可能になり、読者は将来の診療を形成する可能性が最も高い論文に集中することができます。

10 randomized controlled trials with a total of 1101 patients undergoing treatment for cervical disc degeneration with either polyurethane on titanium unconstrained cervical disc (PTUCD) arthroplasty or anterior cervical discectomy and fusion (ACDF) were included in the present meta-analysis. The study was carried out to clarify conflicting conclusions drawn in previous trials regarding the superiority of one intervention compared to the other. The findings of this report indicated that PTUCD arthroplasty provided greater improvements over ADCF in terms of Neck Disability Index scores, VAS neck and arm pain. PTUCD additionally improved SF-36 component summary scores, levels of adjacent segment disease, and reduced heterotopic ossification, reoperation rates, and adverse events. However, the results of this meta-analysis should be interpreted with caution as a number of outcomes had significant heterogeneity, standard deviations were imputed for some outcome measures, and sensitivity analyses were not clearly reported or conducted for a number of key outcome measures.