One hundred and forty-five elderly patients with musculoskeletal disorders at a moderate-to-high risk of falling were randomized to receive a 16 week aquatic exercise program (n=75) or no intervention (n=70) in order to improve function and their quality of life. Moreover, outcomes of interest included upper and lower body strength and flexibility tests, functional mobility tests, balance, pain perception on a Visual Analog Scale (VAS), and the risk of falls Finally, quality of life was also measured using the World Health Organization Quality of Life Questionnaire-BREF (WHOQOL-Bref) and the World Health Organization Quality of Life Questionnaire-Older Adults Module (WHOQOL-Old). Moreover, outcomes were assessed at baseline and upon completion of the 16 week intervention. Results revealed that improvement over time in all outcomes were statistically significantly greater in the aquatic exercise group compared to the control group (p<0.01 for all).