Anterior Cruciate Ligament Surgery and the Development of Knee Osteoarthritis: A Meta-Analysis .
Impact of anterior cruciate ligament surgery on the development of knee osteoarthritis: A systematic literature review and meta-analysis comparing non-surgical and surgical treatments.
Osteoarthr Cartil Open . 2023 Apr 28;5(3):100366.Three randomized controlled trials, involving a total of 343 patients with anterior cruciate ligament (ACL) injury, were included in this systematic review and meta-analysis comparing ACL surgery (Treatment A) vs. non-surgical treatment (Treatment B). Of the total participants, 180 underwent ACL reconstruction surgery, while 163 received non-surgical treatment. The primary outcome of interest was the development of knee osteoarthritis, which was assessed using the Kellgren-Lawrence scoring system, with a follow-up duration ranging from 2 to 11.1 years. The meta-analysis revealed that the relative risk of knee osteoarthritis was higher after surgery.
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