A Systematic Review and Meta-analysis of Anterior Cruciate Ligament Injury Prevention Programs: Training to Stay in the Game.
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OrthoEvidence Journal (OE Journal) - ACE Report
Epub Ahead of Print
Am J Sports Med. 2026 01-Mar;():. 10.1177/03635465251376670Study Summary
18 studies (9 randomized controlled trials and 9 prospective cohort studies) including 25 166 athletes were included in this systematic review and meta-analysis evaluating anterior cruciate ligament (ACL) injury prevention programs versus standard training or no prevention program. Pooled outcomes of interest included ACL injury incidence, female athlete outcomes, age-specific outcomes (<18 vs ≥18 years), sport-specific outcomes (soccer and handball), and balance board–based interventions. Overall, athletes who participated in ACL injury prevention programs had a substantially lower risk of ACL rupture than controls. Significant reductions were observed across female athletes, younger and older athletes, soccer and handball players, and programs incorporating balance board training. Neuromuscular ACL injury prevention programs significantly reduce ACL injury risk and should be routinely incorporated into athletic training programs to decrease the burden of ACL injuries.
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