Adjunct mesenchymal stem cells to Ilizarov method reduce time to union following tibial nonunion .
Ilizarov method in combination with autologous mesenchymal stem cells from iliac crest shows improved outcome in tibial non-union
Saudi J Biol Sci. 2018 May;25(4):819-82525 patients with a tibial nonunion following open tibial fracture were randomized to the Iliazarov method with or without the addition of an intraosseous autologous mesenchymal stem cell injection (MSC) within the nonunion gap. The primary outcome was time to union. Result demonstrated a significantly shorter time to union in the MSC group compared to the control group.
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