Addition of morphine to periarticular injection increases PONV, without improving pain, after THA .
Effect of periarticular morphine injection for total hip arthroplasty: a randomised, double-blind trial
Hip Int. 2019 May;29(3):245-252.100 patients scheduled for unilateral total hip arthroplasty (THA) were randomized to receive analgesic peri-articular cocktail injection containing ropivacaine, epinephrine, ketoprofen, methylprednisolone sodium, and normal saline, with or without the addition of morphine. The primary outcomes of interest were pain at rest and during motion, measured on a Visual Analog Scale (VAS). Secondary outcomes of interest included nausea on a numeric rating scale (NRS), the number of vomiting cases per person, anti-emetic drug consumption, levels of hemoglobin and C-reactive protein (CRP), range of motion in flexion and abduction, thigh swelling, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and the incidence of complications. Results revealed no significant differences in VAS pain scores, both at rest and during movement, between the morphine and control groups. NRS nausea scores in the first hour post-operation, as well as total metoclopramide consumption, was significantly higher in the morphine group. No significant differences were observed between the two groups in total rescue analgesia consumption, levels of hemoglobin and CRP, WOMAC index scores, range of motion in flexion or abduction, thigh swelling, or the incidence of complications.
Desbloquear el informe ACE completo
Tiene acceso a 4 más artículos GRATUITOS este mes.
Haga clic a continuación para desbloquear y ver este ACE Reports
Desbloquear ahora
Evaluaciones críticas de los últimos ensayos controlados aleatorizados de gran impacto y revisiones sistemáticas en ortopedia
Acceso al contenido del podcast OrthoEvidence, que incluye colaboraciones con el Journal of Bone and Joint Surgery, entrevistas con cirujanos reconocidos internacionalmente y mesas redondas sobre noticias y temas ortopédicos
Suscripción a The Pulse, un boletín quincenal basado en la evidencia y diseñado para ayudarle a tomar mejores decisiones clínicas
Acceso exclusivo a artículos de contenido original, incluidas revisiones sistemáticas propias, y artículos sobre métodos de investigación sanitaria y temas ortopédicos de actualidad
O actualícese hoy mismo y obtenga acceso a todo el contenido de OrthoEvidencepor tan sólo 1,99 $ a la semana.
¿Ya tiene una cuenta? Conectarse
Suscríbase a "El Pulso"
Ortopedia basada en la evidencia directamente a su bandeja de entrada. SUSCRIBIRSE