Local infiltration analgesia for total knee arthroplasty: should ketorolac be added?

This report has been verified by one or more authors of the original publication.

この研究はハイインパクトの可能性があります。 OEのAI駆動型ハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文が持つ可能性の高い影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することが可能になり、読者は将来の診療を形成する可能性が最も高い論文に集中することができます。

60 patients about to receive total knee replacement (TKR) surgery were randomized to determine the efficacy of local infiltration analgesia (LIA) solution with added ketorolac. Patients were assessed for intravenous (IV) morphine patient controlled analgesia (PCA) consumption; time to first IV morphine PCA request after surgery; pain intensity (Visual analog scale VAS) and; length of stay. The study demonstrated that the addition of ketorolac in LIA solution contributes to decreased consumption of IV morphine PCA along with prolonged time to first request of IV PCA morphine. The study also found that pain scores were better for the ketorolac group during the first 48 hours after surgery and that this group also presented with lower oxycodone consumption between 48 and 96 hours after surgery. Home readiness in the ketorolac group patients was superior compared to those in the control group.