ACL reconstruction: Morphine–bupivacaine more effective than tramadol–bupivacaine .
The comparison of intraarticular morphine–bupivacaine and tramadol–bupivacaine in postoperative analgesia after arthroscopic anterior cruciate ligament reconstruction
Knee Surg Sports Traumatol Arthrosc. 2012 Sep;20(9):1839-44. doi: 10.1007/s00167-011-1791-7. Epub 2011 Nov 24.60 male ASA I–II patients undergoing arthroscopic ACL reconstruction were included in this study to compare different postoperative analgesics. Patients were randomized to receive 10 mg morphine and 0.5% bupivacaine, 100 mg tramadol and 0.5% bupivacaine, or 20 ml isotonic saline. The results of this study indicated that intra-articular morphine and bupivacaine provide better pain relief, longer analgesic duration (time until first request for analgesics), less analgesic requirement, and shorter unassisted ambulation and discharge time compared to intra-articular tramadol and bupivacaine.
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