PEDIATRIC ORTHOPAEDICS
2018 AAOS Annual Meeting: Ultrasonographic Guidance Prolotherapy for Osgood-Schlatter Disease: A Prospective Randomized Double-Blind Study
OrthoEvidence Journal (OE Journal) - ACE Report
OE Journal. 2018;6(9):1038 adolescents with 50 knees affected by Osgood-Schlatter disease were randomized to three monthly treatments of either prolotherapy with a dextrose solution, or so sham prolotherapy with saline. Patients were assessed for function on the Victorian Institute of Sport Assessment (VISA) score after 1, 2 and 3 months. Results demonstrated no significant differences between groups at 1, 2, or 3 months, with a significant increase in scores from baseline for both groups.
学会報告
このACE報告は、学会発表または抄録の要約です。提供された情報により、バイアスのリスクや全体的な質の正確な評価を提供することには限界があります。臨床試験が進行中であったり、選択された結果が発表されている可能性があるため、結果を慎重に解釈してください。
なぜ今この研究が必要なのですか？
Osgood-Schlatter disease involves pain and swelling over the tibial tubercle in adolescents, particularly among those involved in sporting activities. Prolotherapy has been investigated for efficacy in various musculoskeletal ailments, though not in the setting of Osgood-Schlatter disease.
主な研究課題は何ですか？
In the treatment of adolescents with Osgood-Schlatter disease, how does efficacy and safety of prolotherapy with dextrose compare to sham prolotherapy with saline, assessed over 3 months of treatment?
重要な知見は？
- VISA scores did not significantly differ between the prolotherapy group and the sham group at either 1 month (76.9+/-20.4 vs. 72.6+/-22.2; p=0.508), 2 months (73.3+/-26.8 vs. 74.6+/-26.7; p=0.874), or 3 months (85.7+/-18.7 vs. 83.2+/-19.8; p=0.658).
- The degree of improvement from baseline after 1 month, 2 months, and 3 months was significant in each group.
最も覚えておくべきことは？
In the treatment of adolescents with Osgood-Schlatter disease, prolotherapy for 3 months with a dextrose solution demonstrated no significant difference in functional outcome when compared to sham prolotherapy.
それが私の患者ケアにどのように影響するか？
The results of this study suggest that prolotherapy with a dextrose solution may demonstrate no clinical advantage over saline for functional improvement in the management of adolescents with Osgood-Schlatter disease.
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