AAOS2017: Liposomal bupivacaine not advantageous for intraarticular analgesia in TKA .
Effectiveness of Intraoperative Bupivacaine Liposome Injectable Suspension for Postoperative Pain Control in Total Knee Arthroplasty: A Prospective, Randomized, Double-blind, Controlled Study
96 patients scheduled for unilateral total knee arthroplasty and managed with intraoperative, intraarticular infiltration analgesia as part of a multimodal analgesia regimen were randomized to injection of a drug mixture with or without liposomal bupivacaine. Patients were assessed postoperatively for narcotic consumption, pain scores, time to the ability to walk 100 feet, and the length of hospital stay. No significant differences between groups were observed for any outcome.
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