One hundred ninety-six patients undergoing aseptic or septic revision total hip arthroplasty were randomized to receive either closed incision negative-pressure therapy (ciNPT) (n=105) or a silver-impregnated dressing (n=91). The primary outcome of interest was the rate of wound complications. Secondary outcomes included type of wound complications, need for reoperation due to wound issues, and comparison of perioperative variables. Outcomes were assessed at 90 days postoperatively. Overall, the results of the study revealed no significant difference in wound complication rates between the ciNPT and control groups (11.7% vs. 12.9%, p=0.95), nor in reoperations for wound-related issues (3.9% vs. 1.1%, p=0.37). These findings suggest ciNPT does not reduce wound complications after revision THA when compared with conventional silver dressings.