AAOS 2016: Oral antibiotics correlated with fewer re-infections after two-stage TJA .
Oral Antibiotics Reduce Reinfection Following 2-Stage Exchange: A Multi-Center, Randomized Controlled Trial
94 patients scheduled to undergo two-stage exchange arthroplasty were randomized to either receive or not receive a 3-month oral antibiotic treatment following completion of second stage reimplantation. The purpose of this study was to determine if an intensive antibiotic therapy would be associated with a lower incidence of re-infection prevention failures, as assessed by a log rank survival curve. Results demonstrated a significantly small percentage of infection prevention failures in patients who received antibiotic therapy after a mean follow-up of 16.3 months.
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