40 adolescent female athletes who participate in football (soccer) or handball were randomized to receive either a neuromuscular training (NMT) programme in addition to regular training or regular training alone (control). The purpose of this study was to determine the effect of this evidence-based injury prevention training programme on neuromuscular and biomechanical risk factors for lower extremity injuries. The findings of this study demonstrated a significantly reduced difference between vastus lateralis and semitendinous muscle EMG preactivity just prior to performing a side cutting exercise. When assessed individually the vastus lateralis preactivity was reduced while the semitendinous and biceps femoris muscle preactivity was increased. Additionally, there were fewer reports of injury in the NMT group compared to the control group during the 12 weeks of treatment.