What Are Long-term Predictors of Outcomes for Lumbar Disc Herniation? A Randomized and Observational Study

This report has been verified by one or more authors of the original publication.

この研究はハイインパクトの可能性があります。 OEのAI駆動型ハイインパクト指標は、論文が掲載されたジャーナルと論文自体の科学的内容の両方からのシグナルを統合することで、論文が持つ可能性の高い影響力を推定します。 最先端の自然言語処理を用いて開発されたOEハイインパクトモデルは、ジャーナルのインパクトファクターのみよりも、研究の将来の引用実績をより正確に予測します。 これにより、臨床的に意義のある研究をより早く認識することが可能になり、読者は将来の診療を形成する可能性が最も高い論文に集中することができます。

474 patients with a lumbar disc herniation were randomized to either undergo surgical treatment via a lumbar discectomy or a nonoperative intervention in order to assess long term outcomes and determine outcome predictors. Patients who refused randomization were enrolled in an observational cohort and contributed follow-up data based on subsequent treatment. Between the randomized groups, differences after 8 years in primary outcomes of pain and function did not significantly differ between operatively and nonoperatively managed patients, though secondary outcomes of leg pain, the Sciatica Bothersome Index, and patient-reported satisfaction and perceived improvement favoured the operative group. In the analysis of possible predictive factors; sequestered fragments, high intensity pain for a period of more than 6 months and a work status including students, homemakers, unemployed, or retired were characteristics suggestive of greater benefit with surgery.