The INSITE Trial: Intramedullary Nailing vs Sliding Hip Screw in Trochanteric Fracture Management
Intramedullary Nailing vs Sliding Hip Screw in Trochanteric Fracture Management: The INSITE Randomized Clinical Trial
JAMA Netw Open. 2023 01-Apr.Exclusive Author Interview
850 patients with trochanteric fractures were randomized to receive surgical fixation using an intramedullary nail (n=423, Gamma3 Stryker) or a sliding hip screw (n=427). The primary outcome of interest was health-related quality of life, measured using the Euro-QoL 5-Dimensions (EQ-5D) scale. Secondary outcomes of interest included the incidence of revision, rate of healing, adverse events, mobility, and hip function. Outcomes were assessed up to 1 year post-operation. The results demonstrated similar quality of life, mobility, function, healing, and safety outcomes between the two groups at 1 year post-operation. Given the lower cost of sliding hip screws, it may offer a viable and effective alternative to intramedullary nailing for this patient population.
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