Riassunto dello studio

Four hundred and fifty-two elderly patients scheduled for proximal femur fracture surgery were randomized to receive daily omega-3 fatty acid capsules or a placebo for 30 days after surgery. The primary outcome of interest included the incidence of pulmonary embolism and deep vein thrombosis (DVT). Secondary outcomes of interest were the incidence of hematoma evacuation, wound bleeding, wound infection with frank pus, and other bleeding events requiring transfusion. All outcomes were measured 30-days post-surgery. The results demonstrated that the incidence of pulmonary embolism (p=0.03) as well as DVT (p=0.04) were both statistically significantly lower in the omega-3 fatty acid group. All secondary outcomes were not statistically significantly different between the two groups at 30-day post-surgery.