General Orthopaedics
Botulinum Toxin A (BTA) for pain and function improvement in osteoarthritis: a systematic review and meta-analysis of clinical efficacy evidence from randomized controlled trials.
Toxicon. 2025 01-Nov;():. 10.1016/j.toxicon.2025.108582

Foot & Ankle
Effects of balance training with visual occlusion on postural control in individuals with chronic ankle instability: A systematic review and meta-analysis of randomized controlled trials.
PM R. 2025 01-Dec;():. 10.1002/pmrj.13413

Arthroplasty
Efficacy and safety of combined lumbar plexus and quadratus lumborum block via Shamrock approach at L3 in total hip arthroplasty: a prospective randomized controlled trial.
Trials. 2025 01-Nov;():. 10.1186/s13063-025-09195-w

Pediatric Orthopaedics
Surgical fixation versus non-surgical care for children with a displaced medial epicondyle fracture of the elbow (the SCIENCE study): a multicentre, randomised controlled, superiority trial and economic evaluation
The Lancet. 2025 01-Jan;():. doi: 10.1016/S0140-6736(25)02098-7.

Arthroplasty
Efficacy and Safety of Tranexamic Acid Combined with Absorbable Hemostat in Reducing Perioperative Blood Loss in Total Knee Arthroplasty: A Prospective, Blinded, Randomized Controlled Trial.
J Bone Joint Surg Am. 2025 01-Oct;():. 10.2106/JBJS.24.01236

Arthroplasty
The Analgesic Efficacy of Liposomal Bupivacaine in Adductor Canal Block Following Knee Arthroplasty: A Single-Center, Prospective, Randomized and Controlled Clinical Trial.
Drug Des Devel Ther. 2025 01-Sep;():. 10.2147/DDDT.S535901

General Orthopaedics
Taichi is medicine: Effects of Taichi exercise on knee fitness and psychological health in older adults with knee osteoarthritis (KOA): A randomized controlled trial.
Medicine (Baltimore). 2025 01-Sep;():. 10.1097/MD.0000000000044612

Arthroplasty
L3 paravertebral block combined with retro-psoas compartment block versus femoral nerve block for postoperative analgesia in total knee arthroplasty: A randomized controlled trial.
Saudi J Anaesth. 2025 01-Sep;():. 10.4103/sja.sja_128_25

General Orthopaedics
The Efficacy of Intravenous Analgesia and Various Nerve Blocks for Pain Management in Elderly Patients With Hip Fractures: A Meta-Analysis.
Orthop Surg. 2025 01-Aug;():. 10.1111/os.70090

Foot & Ankle
Can exercise therapy combined with transcranial direct current stimulation further improve balance ability in individuals with chronic ankle instability? A systematic review and meta-analysis.
Front Physiol. 2025 01-Oct;():. 10.3389/fphys.2025.1681272

Arthroplasty
Impact of continuous nerve block at different iliac fascia compartment regions on postoperative analgesia following total hip arthroplasty: A randomized controlled trial.
Medicine (Baltimore). 2025 01-Sep;():. 10.1097/MD.0000000000044424

Peri-Operative
Efficacy and safety of ultrasonic bone scalpel in posterior cervical expansive open-door laminoplasty for cervical degenerative diseases: A prospective randomized controlled trial.
J Orthop Surg (Hong Kong). 2025 01-Sep;():. 10.1177/10225536251364200

General Orthopaedics
Comparison of Remimazolam versus Dexmedetomidine on Hemodynamics in Older Patients Under Lower Extremity Orthopedic Surgery with Spinal Anesthesia: A Randomized Controlled Trial.
Drug Des Devel Ther. 2025 01-Jul;():. 10.2147/DDDT.S504371

Peri-Operative
Prevention of Pregabalin-Related Side Effects Using Slow Dose Escalation Before Surgery: A Trial in Primary Total Joint Arthroplasty Within the Enhanced Recovery After Surgery Pathway.
J Arthroplasty. 2023 01-Aug;():. 10.1016/j.arth.2023.01.039

General Orthopaedics
Association of ABCB1 C1236T Gene Polymorphisms With the Postoperative Analgesic Effects of Sufentanil and Morphine in Patients With Femoral Fractures.
J Perianesth Nurs. 2025 01-Aug;():. 10.1016/j.jopan.2024.10.017

Spine
Local Anesthesia With 1% Lidocaine Versus General Anesthesia for Percutaneous Endoscopic Interlaminar Discectomy at L5/S1 Disc Herniation: A Prospective Randomized Study.
Clin Spine Surg. 2025 01-Aug;():. 10.1097/BSD.0000000000001743

Spine
Platelet-rich plasma for the treatment of discogenic low back pain: a prospective randomized controlled trial.
Front Pain Res (Lausanne). 2025 01-Aug;():. 10.3389/fpain.2025.1648772

General Orthopaedics
Effect of Ciprofol on Postoperative Delirium in Elderly Patients Undergoing Hip Surgery: A Randomized Controlled Trial.
Drug Des Devel Ther. 2025 01-Jul;():. 10.2147/DDDT.S524319

General Orthopaedics
Effects of Intrathecal Sufentanil at Different Doses on Postoperative Pain Relief and Opioid Consumption in Elderly Patients Undergoing Lower Limb Orthopedic Surgery: A Randomized Controlled Trial.
J Pain Res. 2025 01-May;():. 10.2147/JPR.S512653

Osteoarthritis
Psychosocial and physiological health outcomes of outdoor green exercise versus indoor exercise in knee osteoarthritis patients coexisting with type 2 diabetes mellitus: a randomized controlled trial.
Front Endocrinol (Lausanne). 2025 01-May;():. 10.3389/fendo.2025.1560536