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Recombinant human bone morphogenetic protein-7 ineffective in spinal fusion vs. control

Global Spine J. 2016 Mar;6(2):124-32

Meta-analysis Spine Axial Skeleton Bone Morphogenetic Protein Control ICBG Iliac Crest Bone Graft Local Bone Recombinant Revision Spinal Fusion Spine Fusion TCP - Hide

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rhBPM-2 with allograft effective for reconstruction of diaphyseal tibial fractures

J Bone Joint Surg Am. 2006 Jul;88(7):1431-41.

RCT Trauma Bone Tibia Fracture Wyeth Allograft Autogeneous Bone Graft Cortical Recombinant Human Bone Morphogenetic Protein-2 Reconstruction - Hide

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The effect of rhBMP-2 in single-level posterior lumbar interbody arthrodesis

J Bone Joint Surg Am. 2013 May 15;95(10):873-80. doi: 10.2106/JBJS.L.00137

RCT Spine Discs Sciatica Spondylolisthesis Lumbar Bone Iliac Instrumentation Rod System Instrumented Interbody Arthrodesis Polyetheretherketone Cages Recombinant Human Bone Morphogenetic Protein-2 Titanium - Hide

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Lumbar fusion: rhBMP-2 reduces rate of fusion failure and reoperation

Arch Orthop Trauma Surg. 2012 Dec;132(12):1725-40. doi: 10.1007/s00402-012-1607-3. Epub 2012 Sep 1

Meta-analysis Spine Lumbar Bone Iliac Autogenous Iliac Crest Bone Graft Fusion ICBG Recombinant Human Bone Morphogenetic Protein-2 - Hide

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ISASS: Use of rhBMP-2 and autologous bone in PLIF display similar clinical outcomes

RCT Spine Lumbar Autologous Bone Filled PEEK Cages PLIF Recombinant Human Bone Morphogenic Protein - Hide

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E. coli-derived rhBMP-2 offers similar fusion success to AIBG in posterolateral lumbar fusion

Spine J. 2017 Dec;17(12):1866-1874

RCT Spine Spondylolisthesis Stenosis Axial Skeleton Lumbar Iliac Spondylolysis Spinal Stenosis BioAlpha CGBio Inc AIBG Posterolateral Bone Graft Crest Fusion Recombinant Human Bone Morphogenetic Protein-2 - Hide

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Efficacy and safety of rhBMP-2 compared to iliac crest bone graft in spinal fusion

Ann Intern Med. 2013 Jun 18;158(12):877-89. doi: 10.7326/0003-4819-158-12-201306180-00005

Meta-analysis Spine Axial Skeleton Bone Iliac Medtronic Bone Grafts Fusion Surgery ICBG Iliac Crest Bone Graft IPD Observational Recombinant Human Bone Morphogenetic Protein-2 Spinal Fusion - Hide

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rhBMP-7 results in higher union rates compared to PRP in treatment of long bone non-unions

Injury. 2008 Dec;39(12):1391-402. Epub 2008 Nov 22

RCT Trauma Fracture Platelet-Rich Plasma PRP Recombinant Bone Morphogenic Protein - Hide

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Retrograde ejaculation in anterior lumbar surgery with or without rhBMP-2

J Neurosurg Spine. 2013 Feb;18(2):112-21. doi: 10.3171/2012.10.SPINE11908. Epub 2012 Nov 30

Meta-analysis Spine Discs Spondylolisthesis Lumbar Medtronic Factors Implants Nonoperative Recombinant Human Bone Morphogenetic Protein-2 Retrograde - Hide

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Osteogenic protein-1 is safe and effective in the treatment of tibial nonunion

J Bone Joint Surg Am. 2001;83-A Suppl 1(Pt 2):S151-8

RCT Trauma Bone Tibia Fracture Nonunion Stryker Bone Autograft Intramedullary Nailing Protein-1 - Hide

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Bone morphogenetic protein vs. autologous iliac crest bone graft in lumbar fusion surgery

PLoS One. 2014 Jun 2;9(6):e97049. doi: 10.1371/journal.pone.0097049. eCollection 2014.

Meta-analysis Spine Axial Skeleton Lumbar Bone Iliac Autogenous Iliac Crest Bone Graft Autologous Iliac Crest Bone Graft Bone Grafts Bone Morphogenetic Protein Fusion Surgery ICBG Protein-1 Spinal Fusion - Hide

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Intramedullary nailing of closed tibial fracture: rhBMP2-CPM augmentation not recommended

J Bone Joint Surg Am. 2013 Dec 4;95(23):2088-96. doi: 10.2106/JBJS.L.01545

RCT Trauma Bone Tibia Fracture Wyeth Augmentation Bone Morphogenetic Protein Calcium Phosphate CPM Fixation Locked Intramedullary Nail Matrix Reaming Recombinant SOC - Hide

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Iron combined with recombinant human erythropoietin: reduces anemia following TKA surgery

Transfusion. 2011 Jan;51(1):118-24

RCT Arthroplasty Women Lower Extremity Knee Bilateral Control Iron Recombinant Human Erythropoietin Rhuepo TKA Surgery Transfusion - Hide

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Bone Morphogenetic Protein-2 vs Iliac Crest Bone Grafting for Posterolateral Lumbar Spine Fusion

Int J Clin Pract. 2021 01-Apr;():. 10.1111/ijcp.13911

Meta-analysis Spine Axial Skeleton Graft Iliac Crest Bone Graft Recombinant Human Bone Morphogenetic Protein-2 Lumbar Spine Growth factor - Hide

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COA: Use of rhPDGF in a collagen matrix effective for foot and ankle fusion

RCT Foot & Ankle Foot Lower Extremity Ankle Augment Injectable Bone Graft Augment Autogenous Bone Graft Collagen Matrix Factor Fusion Injectable Platelet Standard Internal Fixation - Hide

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rhBMP -12/absorbable collagen sponge is a safe & feasible adjuvant for rotator cuff repair

Am J Sports Med. 2015 Jun 1. pii: 0363546515584756

RCT Shoulder & Elbow Upper Extremity Muscle Rotator Cuff Tear Tears Pfizer Absorbable Collagen Sponge ACS Control Recombinant Human Bone Morphogenetic Protein-12 Standard Of Care - Hide

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rhBMP-2 provides no benefit in treatment of open tibial fractures with a reamed IM nail

J Bone Joint Surg Am. 2011 May 4;93(9):801-8. Epub 2011 Mar 31.

RCT Trauma Bone Tibia Shaft Fracture Pfizer Wyeth Collagen Sponge Intramedullary Nail Fixation Reamed Recombinant Human Bone Morphogenetic Protein-2 Standard Of Care - Hide

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rhBMP-2 is safe and improves outcomes in open tibial fractures

J Bone Joint Surg Am. 2002 Dec;84-A(12):2123-34

RCT Trauma Bone Tibia Fracture Wyeth Control Intramedullary Standard Of Care - Hide

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Recombinant human growth hormone injection does not improve healing rate versus control in RC repair

J Shoulder Elbow Surg. 2018 May;27(5):777-785

RCT Shoulder & Elbow Upper Extremity Muscle Rotator Cuff Tear Arthroscopic Injection Control Recombinant Human Growth Hormone - Hide

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Preoperative human recombinant erythropoietin reduces allogenic blood transfusion

Int Orthop. 2012 Apr;36(4):703-9. Epub 2011 Oct 1.

RCT General Orthopaedics Lower Extremity Hip Arthroplasty Blood Erythropoietin Iron Oral Preoperative Recombinant Rhu-EPO - Hide

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Recombinant human bone morphogenetic protein-7 ineffective in spinal fusion vs. control

rhBPM-2 with allograft effective for reconstruction of diaphyseal tibial fractures

The effect of rhBMP-2 in single-level posterior lumbar interbody arthrodesis

Lumbar fusion: rhBMP-2 reduces rate of fusion failure and reoperation

ISASS: Use of rhBMP-2 and autologous bone in PLIF display similar clinical outcomes

E. coli-derived rhBMP-2 offers similar fusion success to AIBG in posterolateral lumbar fusion

Efficacy and safety of rhBMP-2 compared to iliac crest bone graft in spinal fusion

rhBMP-7 results in higher union rates compared to PRP in treatment of long bone non-unions

Retrograde ejaculation in anterior lumbar surgery with or without rhBMP-2

Osteogenic protein-1 is safe and effective in the treatment of tibial nonunion

Bone morphogenetic protein vs. autologous iliac crest bone graft in lumbar fusion surgery

Intramedullary nailing of closed tibial fracture: rhBMP2-CPM augmentation not recommended

Iron combined with recombinant human erythropoietin: reduces anemia following TKA surgery

Bone Morphogenetic Protein-2 vs Iliac Crest Bone Grafting for Posterolateral Lumbar Spine Fusion

COA: Use of rhPDGF in a collagen matrix effective for foot and ankle fusion

rhBMP -12/absorbable collagen sponge is a safe & feasible adjuvant for rotator cuff repair

rhBMP-2 provides no benefit in treatment of open tibial fractures with a reamed IM nail

rhBMP-2 is safe and improves outcomes in open tibial fractures

Recombinant human growth hormone injection does not improve healing rate versus control in RC repair

Preoperative human recombinant erythropoietin reduces allogenic blood transfusion

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