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Cross-linked formulation of hyaluronic acid provides long term pain relief

Osteoarthritis Cartilage. 2012 May;20(5):350-6. Epub 2012 Feb 1

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain Seikagaku Gel-200 Injection Gel Hyaluronic Acid Phosphate Saline - Hide

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Ketoprofen gel effective for acute pain reduction following ankle sprain

Foot Ankle Int. 2016 Sep;37(9):989-93

RCT Foot & Ankle Lower Extremity Ankle Pain Sprain Ketoprofen Gel Placebo Gel Reduction Topical Ketoprofen - Hide

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Topical drug-free therapy more effective than oral NSAID ketoprofen for muscle soreness

J Sports Sci. 2016 Jan;34(1):88-95.

RCT Sports Medicine Pain IDEA AG Drug-Free Exercise Gel NSAID Oral Topical Ketoprofen Transfersome - Hide

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Silicone gel has no effect on scar pain and pruritus following TKA

Arch Orthop Trauma Surg. 2014 Apr;134(4):555-9

RCT General Orthopaedics Osteoarthritis Scar Lower Extremity Knee Arthritis Pain Gel Placebo Silicone TKA - Hide

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Assessing the efficacy of topical ketoprofen versus active- and placebo-comparators for knee OA

Rheumatology (Oxford). 2013 Jul;52(7):1303-12

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain IDEA AG Gel Oral Celecoxib Placebo Topical Ketoprofen Transfersome Vehicle - Hide

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Effect of autologous platelet gel on cervical spine surgery depends on spinal condition

J Neurosurg Spine. 2007 Nov;7(5):496-502

RCT Spine Discs Hernia Axial Skeleton Cervical Osteophytes DePuy Johnson & Johnson Allograft Autologous Platelet Gel Control Discectomy Fusion Internal Fixation Platelet Concentrate Plating - Hide

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Less pain and faster healing of trauma wounds with platelet-rich plasma gel

Injury. 2009 Aug;40(8):801-5. Epub 2008 Aug 13

RCT Trauma Wound Pain Conventional Methods Platelet-Rich Plasma PRP Gel - Hide

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Knee OA: Single (1200 mg) and 3/day (400 mg) dose chondroitin are equivalent

Osteoarthritis Cartilage. 2012 Oct 8. pii: S1063-4584(12)00992-2. doi: 10.1016/j.joca.2012.09.017

RCT Osteoarthritis Lower Extremity Knee Arthritis Innovative Neurotronics Paracetamol Chondroitin Gel Oral Placebo Sulfate - Hide

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Osteoinductive gel: Faster clinical and functional outcomes in hip replacement

Current Orthopaedic Practice: November/December 2009 - Volume 20 - Issue 6 - pp 655-659

RCT Arthroplasty Osteoarthritis Lower Extremity Hip Arthritis Fixation Gel Replacement - Hide

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Topical NSAIDs demonstrate significant reduction in pain versus placebo for treatment of knee OA

J Rheumatol. 2006 Sep;33(9):1841-4

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Inflammation Pain Gel Non-Steroid Nonsteroidal NSAID Ointment Placebo Reduction Topical Nsaids - Hide

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Collagen hydrolysate supplements may improve articular pain

Complement Ther Med. 2012 Jun;20(3):124-30. doi: 10.1016/j.ctim.2011.12.007. Epub 2012 Jan 20

RCT General Orthopaedics Pain Collagen Hydrolysate Hard Gel Placebo - Hide

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Use of CMC/PEO gel after lumbar discectomy effective in improving low-back and leg pain

Arch Orthop Trauma Surg. 2013 Apr 6

RCT Spine Discs Hernia Back Lumbar Pain Herniation Radiculopathy Medtronic Adhesion Control Discectomy Gel Laminotomy - Hide

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Autologous platelet gel not effective in lowering recovery time/pain after toenail surgery

J Foot Ankle Surg. 2010 Jul-Aug;49(4):385-9. doi: 10.1053/j.jfas.2010.04.019. Epub 2010 Jun 3

RCT Foot & Ankle Foot Wound Lower Extremity Bone Hallux Pain Nitrofurazone APG Autologous Platelet Gel Control - Hide

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Modified unloading walking shoe vs. conventional walking shoe for management of knee OA

Ann Intern Med. 2016 Jul 12

RCT Osteoarthritis Lower Extremity Knee Arthritis GEL-Odyssey GEL-Melbourne OA Conventional Walking Shoes Gel Unloading Walking Shoes - Hide

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Autologous platelet gel does not have a clinically relevant effect in TKA

Knee Surg Sports Traumatol Arthrosc. 2011 Jan;19(1):115-21. doi: 10.1007/s00167-010-1207-0. Epub 2010 Jul 18

RCT Arthroplasty Osteoarthritis Lower Extremity Knee Arthritis APG Autologous Platelet Gel Control Implantation Prosthesis TKA - Hide

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No clinical benefit observed for platelet-rich plasma in ACL-reconstruction

Arthroscopy. 2009 Nov;25(11):1206-13.

RCT Sports Medicine Bone Patella Joint Ligament Muscle Patellar Tendon Anterior Cruciate Bone-Patellar Tendon-Bone Allograft Reconstruction Platelet-Enriched Gel Platelet-Rich Plasma - Hide

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Efficacy of topical diclofenac preparation in managing symptomatic knee osteoarthritis

CMAJ. 2004 Aug 17;171(4):333-8

RCT Osteoarthritis Lower Extremity Knee Arthritis Dimethaid Health Care Control Diclofenac Sodium Topical Diclofenac Vehicle - Hide

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Local Heat Therapy versus Cold Rub Gel For Knee Osteoarthritis

Clin Nurs Res. 2022 01-Jul;():. 10.1177/10547738211035502

RCT Osteoarthritis

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PRP reduces donor site knee pain in bone-patellar tendon-bone ACL reconstruction

Knee Surg Sports Traumatol Arthrosc. 2012 Jan;20(1):114-20. doi: 10.1007/s00167-011-1570-5. Epub 2011 Jun 16

RCT General Orthopaedics Lower Extremity Knee Bone Patella Joint Ligament Muscle Patellar Tendon Pain Bone-Patellar Tendon-Bone Gel Harvesting Platelet-Rich Plasma PRP Reconstruction - Hide

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The efficacy & safety of various doses of fulranumab vs placebo for chronic LBP

Clin Ther. 2016 Jun;38(6):1435-50

RCT Spine Low Back Axial Skeleton Back Pain Amgen Injection Fulranumab Placebo - Hide

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Cross-linked formulation of hyaluronic acid provides long term pain relief

Ketoprofen gel effective for acute pain reduction following ankle sprain

Topical drug-free therapy more effective than oral NSAID ketoprofen for muscle soreness

Silicone gel has no effect on scar pain and pruritus following TKA

Assessing the efficacy of topical ketoprofen versus active- and placebo-comparators for knee OA

Effect of autologous platelet gel on cervical spine surgery depends on spinal condition

Less pain and faster healing of trauma wounds with platelet-rich plasma gel

Knee OA: Single (1200 mg) and 3/day (400 mg) dose chondroitin are equivalent

Osteoinductive gel: Faster clinical and functional outcomes in hip replacement

Topical NSAIDs demonstrate significant reduction in pain versus placebo for treatment of knee OA

Collagen hydrolysate supplements may improve articular pain

Use of CMC/PEO gel after lumbar discectomy effective in improving low-back and leg pain

Autologous platelet gel not effective in lowering recovery time/pain after toenail surgery

Modified unloading walking shoe vs. conventional walking shoe for management of knee OA

Autologous platelet gel does not have a clinically relevant effect in TKA

No clinical benefit observed for platelet-rich plasma in ACL-reconstruction

Efficacy of topical diclofenac preparation in managing symptomatic knee osteoarthritis

Local Heat Therapy versus Cold Rub Gel For Knee Osteoarthritis

PRP reduces donor site knee pain in bone-patellar tendon-bone ACL reconstruction

The efficacy & safety of various doses of fulranumab vs placebo for chronic LBP

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