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Musculoskeletal Evidence
Spine
Chondrolyase For The Treatment of Pain In Patients With Lumbar Disc Herniation
Chondrolyase For The Treatment of Pain In Patients With Lumbar Disc Herniation
Osteoarthritis
The efficacy of metformin for pain, function, and quality of life in knee osteoarthritis: A systematic review and meta-analysis.
Semin Arthritis Rheum. 2026 01-Apr;():. 10.1016/j.semarthrit.2025.152908
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
The efficacy of metformin for pain, function, and quality of life in knee osteoarthritis: A systematic review and meta-analysis.
Semin Arthritis Rheum. 2026 01-Apr;():. 10.1016/j.semarthrit.2025.152908
Arthroplasty
Duloxetine Improves Early Clinical Outcomes Including Range of Motion, Functional Scores, Pain, and Psychological Distress After Arthroscopic Rotator Cuff Repair in Patients With Anxiety or Depression: Prospective Randomized Controlled Trial.
Am J Sports Med. 2026 01-Apr;():. 10.1177/03635465261430918
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Duloxetine Improves Early Clinical Outcomes Including Range of Motion, Functional Scores, Pain, and Psychological Distress After Arthroscopic Rotator Cuff Repair in Patients With Anxiety or Depression: Prospective Randomized Controlled Trial.
Am J Sports Med. 2026 01-Apr;():. 10.1177/03635465261430918
Spine
Comparison of intravenous pethidine and sublingual buprenorphine on postoperative pain severity in patients with vertebral fracture surgery: a randomized multicenter, double-blind controlled trial.
Ann Med Surg (Lond). 2026 01-Feb;():. 10.1097/MS9.0000000000004551
Comparison of intravenous pethidine and sublingual buprenorphine on postoperative pain severity in patients with vertebral fracture surgery: a randomized multicenter, double-blind controlled trial.
Ann Med Surg (Lond). 2026 01-Feb;():. 10.1097/MS9.0000000000004551
Spine
One Spinal Manipulation Session Does Not Affect Static, Quasi-Static and Dynamic Balance or Pressure Pain Threshold in Individuals With Chronic Low Back Pain: A Randomized Clinical Controlled Trial.
Musculoskeletal Care. 2026 01-Mar;():. 10.1002/msc.70202
One Spinal Manipulation Session Does Not Affect Static, Quasi-Static and Dynamic Balance or Pressure Pain Threshold in Individuals With Chronic Low Back Pain: A Randomized Clinical Controlled Trial.
Musculoskeletal Care. 2026 01-Mar;():. 10.1002/msc.70202
Shoulder & Elbow
Efficacy of Standardized Physical Therapy and Axillary Motor Stimulation for Chronic Shoulder Pain: A Randomized Controlled Trial.
Am J Phys Med Rehabil. 2026 01-Mar;():. 10.1097/PHM.0000000000002863
Efficacy of Standardized Physical Therapy and Axillary Motor Stimulation for Chronic Shoulder Pain: A Randomized Controlled Trial.
Am J Phys Med Rehabil. 2026 01-Mar;():. 10.1097/PHM.0000000000002863
Spine
DMA Clinical Pilates(TM) exercises improved clinical and biomechanical outcomes for adults with nonspecific chronic low back pain: a randomized controlled trial.
Disabil Rehabil. 2026 01-Mar;():. 10.1080/09638288.2025.2563762
DMA Clinical Pilates(TM) exercises improved clinical and biomechanical outcomes for adults with nonspecific chronic low back pain: a randomized controlled trial.
Disabil Rehabil. 2026 01-Mar;():. 10.1080/09638288.2025.2563762
Shoulder & Elbow
Plasma-Rich Plasma Does Not Improve Pain or Function in Patients with Lateral Epicondylitis Compared to Placebo
Plasma-Rich Plasma Does Not Improve Pain or Function in Patients with Lateral Epicondylitis Compared to Placebo
Arthroplasty
Optimizing Postoperative Pain Management in Total Knee Arthroplasty With Preoperative Methadone: A Prospective, Randomized Study.
J Arthroplasty. 2026 01-Feb;():. 10.1016/j.arth.2025.06.058
Optimizing Postoperative Pain Management in Total Knee Arthroplasty With Preoperative Methadone: A Prospective, Randomized Study.
J Arthroplasty. 2026 01-Feb;():. 10.1016/j.arth.2025.06.058
Trauma
Comparing a Multimodal Pain Protocol versus Hydrocodone- Acetaminophen After Outpatient Orthopaedic Trauma Surgeries: A Randomized Controlled Trial
Comparing a Multimodal Pain Protocol versus Hydrocodone- Acetaminophen After Outpatient Orthopaedic Trauma Surgeries: A Randomized Controlled Trial
Trauma
Therapist delivered massage for Veterans with chronic neck pain: a randomized control trial.
Pain Med. 2026 01-Feb;():. 10.1093/pm/pnaf118
Therapist delivered massage for Veterans with chronic neck pain: a randomized control trial.
Pain Med. 2026 01-Feb;():. 10.1093/pm/pnaf118
Osteoarthritis
Effectiveness of genicular nerve block on pain and disability in chronic knee osteoarthritis: a randomized double blinded placebo controlled trial.
Clin Rheumatol. 2026 01-Feb;():. 10.1007/s10067-025-07818-w
Effectiveness of genicular nerve block on pain and disability in chronic knee osteoarthritis: a randomized double blinded placebo controlled trial.
Clin Rheumatol. 2026 01-Feb;():. 10.1007/s10067-025-07818-w
Physical Therapy & Rehab
Does radial shockwave therapy lead to immediate improvements in pain in people with insertional Achilles tendinopathy? A randomised controlled trial.
Clin Rehabil. 2026 01-Feb;():. 10.1177/02692155251394951
Does radial shockwave therapy lead to immediate improvements in pain in people with insertional Achilles tendinopathy? A randomised controlled trial.
Clin Rehabil. 2026 01-Feb;():. 10.1177/02692155251394951
Spine
Music therapy and Benson relaxation in postoperative care: A randomized controlled trial on pain and kinesiophobia after lumbar discectomy.
Explore (NY). 2026 01-Mar;():. 10.1016/j.explore.2025.103311
Music therapy and Benson relaxation in postoperative care: A randomized controlled trial on pain and kinesiophobia after lumbar discectomy.
Explore (NY). 2026 01-Mar;():. 10.1016/j.explore.2025.103311
Arthroplasty
Intraoperative Genicular Nerve Infiltration Offers Comparable Pain Control to Traditional Periarticular Injection After Total Knee Arthroplasty: A Randomized Controlled Trial.
Arthroplast Today. 2026 01-Feb;():. 10.1016/j.artd.2025.101927
Intraoperative Genicular Nerve Infiltration Offers Comparable Pain Control to Traditional Periarticular Injection After Total Knee Arthroplasty: A Randomized Controlled Trial.
Arthroplast Today. 2026 01-Feb;():. 10.1016/j.artd.2025.101927
Spine
Effectiveness of Jaw Exercises Applied in Addition to Cervical Stabilization Exercises in Individuals with Chronic Neck Pain: A Randomized Controlled Trial.
J Pain Res. 2026 01-Feb;():. 10.2147/JPR.S584088
Effectiveness of Jaw Exercises Applied in Addition to Cervical Stabilization Exercises in Individuals with Chronic Neck Pain: A Randomized Controlled Trial.
J Pain Res. 2026 01-Feb;():. 10.2147/JPR.S584088
Spine
Multimodal analgesia and the erector spinae plane block in a rapid recovery pathway after posterior spinal fusion in adolescent idiopathic scoliosis: a randomized controlled study of practicality.
Reg Anesth Pain Med. 2026 01-Feb;():. 10.1136/rapm-2024-105748
Multimodal analgesia and the erector spinae plane block in a rapid recovery pathway after posterior spinal fusion in adolescent idiopathic scoliosis: a randomized controlled study of practicality.
Reg Anesth Pain Med. 2026 01-Feb;():. 10.1136/rapm-2024-105748
Arthroplasty
Popliteal plexus block in total knee arthroplasty: a single-center randomized controlled double-blinded trial.
Reg Anesth Pain Med. 2026 01-Mar;():. 10.1136/rapm-2024-105782
Popliteal plexus block in total knee arthroplasty: a single-center randomized controlled double-blinded trial.
Reg Anesth Pain Med. 2026 01-Mar;():. 10.1136/rapm-2024-105782
Arthroplasty
No short term pain benefit of adding corticosteroids to periarticular analgesia after total knee arthroplasty: a prospective, double-blind, randomized controlled trial.
J Orthop Surg Res. 2026 01-Feb;():. 10.1186/s13018-025-06575-5
No short term pain benefit of adding corticosteroids to periarticular analgesia after total knee arthroplasty: a prospective, double-blind, randomized controlled trial.
J Orthop Surg Res. 2026 01-Feb;():. 10.1186/s13018-025-06575-5
Physical Therapy & Rehab
Impact of gluteus maximus-focused intervention using Powers' program on chronic mechanical low back pain: A randomized controlled trial.
BMC Sports Sci Med Rehabil. 2026 01-Jan;():. 10.1186/s13102-025-01475-x
Impact of gluteus maximus-focused intervention using Powers' program on chronic mechanical low back pain: A randomized controlled trial.
BMC Sports Sci Med Rehabil. 2026 01-Jan;():. 10.1186/s13102-025-01475-x
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