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NSAIDs associated with reduction in heterotopic ossification development versus placebo in THA

Bone Joint J. 2018 Jul;100-B(7):915-922. doi: 10.1302/0301-620X.100B7.BJJ-2017-1467.R1

Meta-analysis Arthroplasty Lower Extremity Hip Inflammation NSAID Nsaids Placebo Prophylaxis Reduction THA - Hide

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NSAID vs. steroid injection: equally effective in treating trigger digit at 3 months

J Hand Surg Am. 2012 Jul;37(7):1319-23

RCT Hand & Wrist Diabetes Finger Trigger Finger Upper Extremity Triamcinolone Steroid Injection Corticosteroid Injection NSAID - Hide

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COA/ICORS2019: NSAID use >4wks, especially indomethacin, associated with non-union in bone fractures

Meta-analysis General Orthopaedics Fracture Indomethacin NSAID Nsaids - Hide

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NSAID significantly reduces incidence of heterotopic ossification after hip arthroscopy

J Bone Joint Surg Am. 2015 Dec 16;97(24):2032-7

RCT Sports Medicine Lower Extremity Hip Femoroacetabular Impingement Impingement Naproxen Arthroscopy NSAID Placebo Prophylaxis - Hide

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AAOS2017: NSAID does not impair pediatric long bone fracture healing

RCT Pediatric Orthopaedics Fracture Ibuprofen Acetaminophen Analgesia Regimen NSAID - Hide

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NSAIDs reduce pain in the short-term when used to treat patients with knee osteoarthritis

BMJ. 2004 Dec 4;329(7478):1317

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Inflammation Pain Celecoxib Diclofenac Naproxen Rofecoxib Etodolac Lumiracoxib Meloxicam Valdecoxib Nabumetone Oxaprozin Flurbiprofen Tiaprofenic Acid Diflunisal Analgesic Inhibitor NSAID Nsaids Placebo - Hide

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Celecoxib and aceclofenac reduce COX-2 and mPEGS-1 expression in osteoarthritic patients

Osteoarthritis Cartilage. 2008 Dec;16(12):1484-93. Epub 2008 Jun 10

RCT General Orthopaedics Osteoarthritis Lower Extremity Knee Arthritis Cartilage Celecoxib Aceclofenac - Hide

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Celecoxib vs. diclofenac plus omeprazole for OA or RA treatment with lesser GI risk

Lancet. 2010 Jul 17;376(9736):173-9. Epub 2010 Jun 16

RCT Osteoarthritis Arthritis Pfizer Celecoxib Diclofenac Omeprazole - Hide

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Topical drug-free therapy more effective than oral NSAID ketoprofen for muscle soreness

J Sports Sci. 2016 Jan;34(1):88-95.

RCT Sports Medicine Pain IDEA AG Drug-Free Exercise Gel NSAID Oral Topical Ketoprofen Transfersome - Hide

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Topical NSAIDs demonstrate significant reduction in pain versus placebo for treatment of knee OA

J Rheumatol. 2006 Sep;33(9):1841-4

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Inflammation Pain Gel Non-Steroid Nonsteroidal NSAID Ointment Placebo Reduction Topical Nsaids - Hide

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Network meta-analysis of 20 NSAIDs in treatment of anyklosing spondylitis

Ann Rheum Dis. 2016 Jun;75(6):1152-60

Meta-analysis Spine Inflammation Spondylitis Nsaids Placebo - Hide

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NSAID injection of ketorolac improved UCLA scores & passive abduction in patients with SIS

J Shoulder Elbow Surg. 2013 May;22(5):595-601. doi: 10.1016/j.jse.2012.08.026. Epub 2012 Nov 22

RCT Shoulder & Elbow Upper Extremity Shoulder Bone Subacromial Inflammation Pain Bursitis Impingement Syndrome Lidocaine Epinephrine Triamcinolone Ketorolac Posterolateral Corticosteroid Nonsteroidal NSAID Subacromial Injection - Hide

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Single intra-articular corticosteroid injection vs oral NSAID for adhesive capsulitis

Am J Sports Med. 2016 Feb;44(2):474-81

RCT Shoulder & Elbow Capsulitis Upper Extremity Inflammation Pain Diclofenac Adhesive Corticosteroid Injection NSAID Oral Nsaids - Hide

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NSAIDs versus acetaminophen for treatment of knee and hip osteoarthritis

Osteoarthritis Cartilage. 2011 Aug;19(8):921-9

Meta-analysis Osteoarthritis Lower Extremity Hip Knee Arthritis Inflammation Pain Acetaminophen Factors Impact NSAID Nsaids - Hide

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AAOS2019: IA corticosteroid versus NSAID in knee osteoarthritis treatment

RCT Osteoarthritis Lower Extremity Knee Arthritis Methylprednisolone Ketorolac Corticosteroid Intraarticular Injection NSAID - Hide

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Non-invasive interactive neuro-stimulation improves short-term outcome in athletes with ankle sprain

J Foot Ankle Surg. 2019 May;58(3):441-446. doi: 10.1053/j.jfas.2018.09.009

RCT Foot & Ankle Athletes Lower Extremity Ankle Sprain Etoricoxib Non-Invasive Interactive Neurostimulation Sham - Hide

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Oral NSAIDs versus opioids for pain management of patients with knee OA

Osteoarthritis Cartilage. 2016 Jun;24(6):962-72

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Inflammation Pain Ibuprofen Celecoxib Fentanyl Diclofenac Naproxen Tramadol Etodolac Hydromorphone Morphine Piroxicam Hydrocodone Oxycodone Methadone Ketoprofen Meloxicam Codeine Nabumetone Flurbiprofen Sulindac Salsalate Indomethacin NSAID Oral Nsaids Reduction - Hide

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THR: Celecoxib more effective than ibuprofen in prevention of heterotopic bone formation

J Bone Joint Surg Br. 2007 Feb;89(2):155-9.

RCT Arthroplasty Osteoarthritis Lower Extremity Hip Arthritis Ibuprofen Celecoxib Inhibitor Prevention Replacement THR - Hide

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Ibuprofen Does Not Impair Long Bone Fracture Healing in Pediatric Fracture Patients

J Pediatr Orthop. 2020 01-Sep;():. 10.1097/BPO.0000000000001603

RCT Pediatric Orthopaedics Appendicular Lower Extremity Lower Extremity Fracture Ibuprofen Acetaminophen NSAID Non-selective NSAID - Hide

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NSAIDs effect on blood pressure safe over 6 weeks in pediatric patients with JIA

Clin Med Insights Pediatr. 2015 May 4;9:55-62

RCT Pediatric Orthopaedics Children Arthritis Pfizer Celecoxib Naproxen Blood Pressure - Hide

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NSAIDs associated with reduction in heterotopic ossification development versus placebo in THA

NSAID vs. steroid injection: equally effective in treating trigger digit at 3 months

COA/ICORS2019: NSAID use >4wks, especially indomethacin, associated with non-union in bone fractures

NSAID significantly reduces incidence of heterotopic ossification after hip arthroscopy

AAOS2017: NSAID does not impair pediatric long bone fracture healing

NSAIDs reduce pain in the short-term when used to treat patients with knee osteoarthritis

Celecoxib and aceclofenac reduce COX-2 and mPEGS-1 expression in osteoarthritic patients

Celecoxib vs. diclofenac plus omeprazole for OA or RA treatment with lesser GI risk

Topical drug-free therapy more effective than oral NSAID ketoprofen for muscle soreness

Topical NSAIDs demonstrate significant reduction in pain versus placebo for treatment of knee OA

Network meta-analysis of 20 NSAIDs in treatment of anyklosing spondylitis

NSAID injection of ketorolac improved UCLA scores & passive abduction in patients with SIS

Single intra-articular corticosteroid injection vs oral NSAID for adhesive capsulitis

NSAIDs versus acetaminophen for treatment of knee and hip osteoarthritis

AAOS2019: IA corticosteroid versus NSAID in knee osteoarthritis treatment

Non-invasive interactive neuro-stimulation improves short-term outcome in athletes with ankle sprain

Oral NSAIDs versus opioids for pain management of patients with knee OA

THR: Celecoxib more effective than ibuprofen in prevention of heterotopic bone formation

Ibuprofen Does Not Impair Long Bone Fracture Healing in Pediatric Fracture Patients

NSAIDs effect on blood pressure safe over 6 weeks in pediatric patients with JIA

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