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Melatonin has no significant effect on sleep and pain after TKA
J Arthroplasty. 2015 Dec;30(12):2370-5
Treatment of osteopenia with melatonin effective in increasing BMD in postmenopausal women
J Pineal Res. 2015 Sep;59(2):221-9.
Melatonin does not reduce the incidence of delirium among elderly hip fracture patients
CMAJ. 2014 Oct 7;186(14):E547-56.
IL-1 receptor antagonist improves knee function of acute knee injuries with an ACL tear
Osteoarthritis Cartilage. 2012 Apr;20(4):271-8. Epub 2012 Jan 10
5-hydroxytryptamine receptor inhibitor is safe and effective for treatment of lumbar disc
J Neurosurg Spine. 2005 Apr;2(4):441-6
No effect of GLP-1 receptor agonists on fracture incidence in type 2 diabetes treatment
J Diabetes. 2014 May;6(3):260-6. doi: 10.1111/1753-0407.12102. Epub 2013 Nov 22
Dronabinol does not cause metabolic disturbances in managing chronic neuropathy pain
Clin Ther. 2015 Oct 1;37(10):2267-74. doi: 10.1016/j.clinthera.2015.07.023
Orthokin effective in improving KOOS symptoms and KOOS sport scores in knee osteoarthritis
Osteoarthritis Cartilage. 2008 Apr;16(4):498-505. Epub 2007 Sep 6.
The effect of adjuvant aromatase inhibitors on BMD in women with breast cancer
Lancet Oncol. 2014 Apr;15(4):474-82. doi: 10.1016/S1470-2045(14)70035-X. Epub 2014 Mar 11
Ronacaleret does not significantly reduce time to healing of distal radius fracture
Bone. 2011 Oct;49(4):845-52. doi: 10.1016/j.bone.2011.06.017. Epub 2011 Jun 30
Dronabinol similar in safety and efficacy as diphenhydramine for neuropathic pain relief
Am J Phys Med Rehabil. 2010 Oct;89(10):840-8. doi: 10.1097/PHM.0b013e3181f1c4ec
Nabilone effective in reducing headache in medication overuse headach patients compared to ibuprofen
J Headache Pain. 2012 Nov;13(8):677-84. doi: 10.1007/s10194-012-0490-1
Dronabinol effective in reducing neuropathic pain in multiple sclerosis after 48-week treatment
Eur Neurol. 2017;78(5-6):320-329.
Ajulemic acid effective in reduction of chronic neuropathic pain, with minimal side effects
Neuropharmacology. 2005 Jun;48(8):1164-71
Inhaled THC demonstrated dose-dependent pain reduction and modest side effect 4 hours post-treatment
J Pain. 2015 Jul;16(7):616-27. doi: 10.1016/j.jpain.2015.03.008
THC effective for muscle stiffness relief due to MS after 12 weeks of treatment compared to placebo
J Neurol Neurosurg Psychiatry. 2012 Nov;83(11):1125-32. doi: 10.1136/jnnp-2012-302468
Methylnaltrexone reduces morphine side effects after orthopedic surgery
Pain Pract. 2015 Apr;15(4):348-54
Tetrahydrocannabinol similar in efficacy & safety as placebo in improving spasticity and pain in MS
Clin Ther. 2018 Sep;40(9):1467-1482. doi: 10.1016/j.clinthera.2017.01.016
Nabilone 1mg per day safe and effective in treating chronic upper motor neuron syndrome
J Neurol. 2006 Oct;253(10):1337-41
Dronabinol increases pain threshold compared to placebo for functional chest pain over 4 weeks
Dis Esophagus. 2017 Feb 1;30(2):1-8. doi: 10.1111/dote.12455