Non-inferior efficacy of topical TXA to IV TXA in total knee arthroplasty patients

J Arthroplasty. 2014 Aug;29(8):1528-31

Combination of intravenous and topical TXA improves outcomes following primary TKA

J Arthroplasty. 2014 Dec;29(12):2342-6.

AAOS 2016: IV+IA TXA significantly reduces blood loss compared to IV TXA alone in TKA

Lower blood loss with IV+IA TXA versus IV TXA alone following total knee arthroplasty

J Bone Joint Surg Am. 2016 May 18;98(10):835-41

Similar blood loss and lower cost with oral TXA vs. both IA TXA and IV TXA in total hip arthroplasty

J Arthroplasty. 2018 Mar;33(3):786-793

Large-scale trial comparing topical and intravenous TXA efficacy in total knee arthroplasty

J Bone Joint Surg Am. 2018 Jun 20;100(12):1023-1029

TXA effective in reducing blood loss and transfusion in TKA vs. routine hemostasis

Arch Orthop Trauma Surg. 2015 Jul;135(7):1017-25

Intracapsular and intravenous administration for TXA similar in efficacy and safety in TKA

J Arthroplasty. 2016 Nov;31(11):2452-2457

Efficacy of combined IV/IA TXA administration in simultaneous bilateral TKA

Knee. 2015 Mar;22(2):131-5

Combined IV-topical TXA more effective than IV TXA alone in total hip and knee arthroplasty

Int J Surg. 2016 Dec;36(Pt A):324-329

Combined IV-topical TXA versus IV TXA alone in patients undergoing revision THA

J Arthroplasty. 2016 Nov;31(11):2548-2553

Topical TXA reduces blood loss compared to IV TXA in bilateral total knee arthroplasty

J Arthroplasty. 2016 Jul;31(7):1442-8

Intravenous and topical tranexamic acid have similar efficacy in TKA

Arch Orthop Trauma Surg. 2015 Apr;135(4):573-88.

IV & topical TXA similarly safe & effective for reducing blood loss and transfusion in TKA

J Orthop. 2016 Mar 26;13(3):127-31

AAOS2017: Blood loss and transfusion rate similar with intravenous and topical TXA in THA

AAOS 2016: Oral and IV TXA demonstrate equivalent efficacy for blood loss in THA

TXA efficacy in perioperative spinal surgery bleeding

Spine J. 2015 Apr 1;15(4):752-761.

Topical and intravenous tranexamic acid equally effective in total knee arthroplasty

Knee. 2014 Dec;21(6):987-993

Postoperative multi-dose oral versus IV TXA in total knee arthroplasty without tourniquet control

Thromb Res. 2018 Nov;171:68-73. doi: 10.1016/j.thromres.2018.09.054

Preop oral TXA demonstrates noninferiority to IV TXA in TKA for hemostasis

J Arthroplasty. 2016 Sep;31(9 Suppl):26-30