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Knee OA - The therapeutic trajectory of corticosteroids and hyaluronic acid

Arthritis Rheum. 2009 Dec 15;61(12):1704-11

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Hyaluronan Corticosteroid Injections Conservative Hyaluronate Hyaluronic Acid Injections Intraarticular Injections Of Hyaluronic Acid Post-Injection Viscosupplementation - Hide

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Hyaluronic acid versus corticosteroid in the treatment of knee osteoarthritis

ACE Review Osteoarthritis

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Intraarticular HA injections effective for muscle strength & pain in knee osteoarthritis

Osteoarthritis Cartilage. 2002 Sep;10(9):680-6

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain Bayer Cybex Injections Control HA Hyaluronic Acid Muscle Strength - Hide

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Hyaluronic acid did not yield superior outcomes for hip osteoarthritis

Arthritis Rheum. 2009 Mar;60(3):824-30

RCT Osteoarthritis Lower Extremity Hip Arthritis Injection Of Hyaluronic Acid Placebo Single Intraarticular Injection - Hide

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HA more effective than placebo in knee OA, no difference between 3 and 6 injections of HA

. 2006 ;():.

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain Bioniche Injections HA Injection Hyaluronic Acid Placebo - Hide

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No difference observed over 1 year between high and low molecular weight HA for knee OA treatment

Hippokratia. 2016 Jan-Mar;20(1):26-31

RCT Osteoarthritis Lower Extremity Knee Arthritis Molecular Weight - Hide

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Hyaluronic acid with and without additional dexamethasone injection for knee OA

Curr Med Res Opin. 1992;13(1):49-55

RCT Osteoarthritis Lower Extremity Knee Arthritis Hyalgan Dexamethasone HA Hyaluronic Acid Intraarticular Injection - Hide

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Efficacy of hyaluronic acid vs placebo for pain relief in knee OA; meta-analysis of RCTs

J Fam Pract. 2005 Sep;54(9):758-67

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Pain Hyaluronic Acid Injections Injections Of Hyaluronic Acid Injections Of Placebo Saline Injection - Hide

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IA versus oral hyaluronic acid in the treatment of patients with KL grade I-II knee osteoarthritis

Musculoskelet Surg. 2017 Apr;101(1):45-49. doi: 10.1007/s12306-016-0428-x

RCT Osteoarthritis Lower Extremity Knee Arthritis Hyaluronic Acid IAHA Oral - Hide

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Intra-articular hyaluronic acid provides longer pain relief as compared to corticosteroid

Exp Ther Med. 2015 Feb;9(2):493-500.

Meta-analysis General Orthopaedics Osteoarthritis Lower Extremity Knee Arthritis Pain Hyaluronan Corticosteroid Flexion HA Hyaluronic Acid Injection Injections Of Hyaluronic Acid - Hide

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AAOS2017: Intraarticular PRP vs HA injections for degenerative knee pathology

RCT Osteoarthritis Lower Extremity Knee Arthritis Chondropathy Injections HA High-Molecular-Weight Hyaluronic Acid Intraarticular Injection Leukocyte-Rich Platelet-Rich Plasma PRP - Hide

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Better early outcome, similar 6-12 month outcome with PRP versus HA for hip osteoarthritis

Int J Surg. 2018 May;53:279-287

Meta-analysis Osteoarthritis Lower Extremity Hip Arthritis HA Hyaluronic Acid Injections Platelet-Rich Plasma Injections Post-Injection PRP - Hide

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Small effect of hyaluronic acid for pain relief in treatment of knee osteoarthrits

JAMA. 2003 Dec 17;290(23):3115-21

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Pain Synvisc Orthovisc Hyaluronic Acid Injections Injections Of Hyaluronic Acid Placebo - Hide

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Comparison of combined hyaluronic acid (HA) and corticosteroid vs. HA alone injection for knee OA

Exp Ther Med. 2018 Sep;16(3):1928-1934. doi: 10.3892/etm.2018.6371

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain Injection - Hide

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Differences in hyaluronic acid characteristics influence outcomes in knee OA patients

Am J Sports Med. 2016 Aug;44(8):2158-65

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Ferring Hylan Hyaluronan Hyaluronic Acid Injections Viscosupplementation - Hide

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Limited efficacy of intra-articular hyaluronic acid in treatment of knee OA

CMAJ. 2005 Apr 12;172(8):1039-43

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Hyaluronan Hyaluronate Hyaluronic Acid Injections Placebo Injections Rest Viscosupplementation - Hide

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Improvement of condition with hyaluronic acid injection for ankle OA

Arch Phys Med Rehabil. 2013 May;94(5):951-60. doi: 10.1016/j.apmr.2012.10.030. Epub 2012 Nov 10

Meta-analysis Osteoarthritis Lower Extremity Ankle Arthritis HA Hyaluronic Acid Injections Viscosupplementation - Hide

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AAOS 2015: MM-II liposome intraarticular injection vs hyaluronic acid for knee OA

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain Hyaluronic Acid Intraarticular Injection Single Injection - Hide

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Assessment of 12-week efficacy between high and low molecular weight HA for knee OA treatment

Clin Ther. 1999 Sep;21(9):1549-62

RCT Osteoarthritis Lower Extremity Knee Arthritis Biomatrix Hylan HA High Molecular Weight Hyaluronic Acid Intraarticular Injections Low Molecular Weight Hyaluronic Acid - Hide

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AAOS: Reporting of hyaluronic acid efficacy in knee OA may be influenced by industry

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Hyaluronic Acid Injections Placebo - Hide

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Knee OA - The therapeutic trajectory of corticosteroids and hyaluronic acid

Hyaluronic acid versus corticosteroid in the treatment of knee osteoarthritis

Intraarticular HA injections effective for muscle strength & pain in knee osteoarthritis

Hyaluronic acid did not yield superior outcomes for hip osteoarthritis

HA more effective than placebo in knee OA, no difference between 3 and 6 injections of HA

No difference observed over 1 year between high and low molecular weight HA for knee OA treatment

Hyaluronic acid with and without additional dexamethasone injection for knee OA

Efficacy of hyaluronic acid vs placebo for pain relief in knee OA; meta-analysis of RCTs

IA versus oral hyaluronic acid in the treatment of patients with KL grade I-II knee osteoarthritis

Intra-articular hyaluronic acid provides longer pain relief as compared to corticosteroid

AAOS2017: Intraarticular PRP vs HA injections for degenerative knee pathology

Better early outcome, similar 6-12 month outcome with PRP versus HA for hip osteoarthritis

Small effect of hyaluronic acid for pain relief in treatment of knee osteoarthrits

Comparison of combined hyaluronic acid (HA) and corticosteroid vs. HA alone injection for knee OA

Differences in hyaluronic acid characteristics influence outcomes in knee OA patients

Limited efficacy of intra-articular hyaluronic acid in treatment of knee OA

Improvement of condition with hyaluronic acid injection for ankle OA

AAOS 2015: MM-II liposome intraarticular injection vs hyaluronic acid for knee OA

Assessment of 12-week efficacy between high and low molecular weight HA for knee OA treatment

AAOS: Reporting of hyaluronic acid efficacy in knee OA may be influenced by industry

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