OrthoEvidence - Search

Spine
Efficacy and safety of upadacitinib, a selective JAK-1 inhibitor in treatment of ankylosing spondylitis: a meta-analysis.
BMC Rheumatol. 2025 01-Feb;():. 10.1186/s41927-025-00467-1

General Orthopaedics

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Association between combined treatment with SGLT2 inhibitors and metformin for type 2 diabetes mellitus on fracture risk: a meta-analysis of randomized controlled trials
Osteoporos Int. 2020 01-Dec;():. 10.1007/s00198-020-05590-y

Shoulder & Elbow
The Effect of NSAIDs and COX-2 Inhibitors on Structural and Clinical Outcomes Following Rotator Cuff Repair – A Systematic Review and Meta Analysis

Osteoarthritis
Efficacy of tumor necrosis factor inhibitors in hand osteoarthritis: A systematic review and meta-analysis of randomized controlled trials.
Osteoarthr Cartil Open. 2023 01-Aug;():. 10.1016/j.ocarto.2023.100404

Shoulder & Elbow
The level of ratio between matrix metalloproteinase-1 (MMP-1) and tissue inhibitor matrix metalloproteinase-1 (TIMP-1) after prolotherapy intervention and the functional outcome in patient with frozen shoulder: A randomized controlled trial.

This report has been verified by one or more authors of the original publication.

Medicine (Baltimore). 2023 01-Jul;():. 10.1097/MD.0000000000034356

Shoulder & Elbow
Do Selective COX-2 Inhibitors Affect Pain Control and Healing After Arthroscopic Rotator Cuff Repair? A Preliminary Study
Am J Sports Med. 2018 Mar;46(3):679-686

Osteoarthritis

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Treatment of osteoarthritis with celecoxib, a cyclooxygenase-2 inhibitor: a randomized controlled trial
Mayo Clin Proc. 1999 Nov;74(11):1095-105

Osteoarthritis

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

Non-steroidal anti-inflammatory drugs, including cyclo-oxygenase-2 inhibitors, in osteoarthritic knee pain: meta-analysis of randomised placebo controlled trials
BMJ. 2004 Dec 4;329(7478):1317

Arthroplasty
A Prospective Randomized Study Comparing Oral Direct Factor Xa Inhibitor with Lowmolecular- weight Heparin for Evaluation of Surgical Wound Complications Following Total Hip Arthroplasty

Osteoarthritis
Omeract-oarsi ‘strict responders’ analysis from results of a randomized, double-blind, placebo-controlled phase 1 study of a novel, intra-articular, injectable, wnt inhibitor (sm04690) in the treatment of osteoarthritis of the knee

Arthroplasty
Safety and efficacy of edoxaban, an oral factor xa inhibitor, for thromboprophylaxis after total hip arthroplasty in Japan and Taiwan
J Arthroplasty. 2014 Dec;29(12):2439-46.

Arthroplasty
Safety and Efficacy of Edoxaban, an Oral Factor Xa Inhibitor, Versus Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty: The STARS E-3 Trial

This report has been verified by one or more authors of the original publication.

Thromb Res. 2014 Dec;134(6):1198-204

Spine
New treatment of lumbar disc herniation involving 5-hydroxytryptamine2A receptor inhibitor: a randomized controlled trial
J Neurosurg Spine. 2005 Apr;2(4):441-6

Metabolic Disorders
High-dose eicosapentaenoic acid and docosahexaenoic acid supplementation reduces bone resorption in postmenopausal breast cancer survivors on aromatase inhibitors: a pilot study

This report has been verified by one or more authors of the original publication.

Nutr Cancer. 2014;66(1):68-76. doi: 10.1080/01635581.2014.847964. Epub 2013 Nov 25

Tumour

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

A randomised trial of electro-acupuncture for arthralgia related to aromatase inhibitor use

This report has been verified by one or more authors of the original publication.

Eur J Cancer. 2014 Jan;50(2):267-76. doi: 10.1016/j.ejca.2013.09.022. Epub 2013 Oct 24

Arthroplasty
Less blood loss under concomitant administration of tranexamic acid and indirect factor Xa inhibitor following total knee arthroplasty: a prospective randomized controlled trial
Knee Surg Sports Traumatol Arthrosc. 2013 Nov;21(11):2611-7

General Orthopaedics
Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor alpha inhibitors (GO-AFTER study): A multicentre, randomised, double-blind, placebo-controlled, phase III trial

This report has been verified by one or more authors of the original publication.

Lancet. 2009 Jul 18;374(9685):210-21. Epub 2009 Jun 26

Arthroplasty
Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery
J Arthroplasty. 2009 Jan;24(1):1-9. Epub 2008 Apr 14

Osteoarthritis

This study has been identified as potentially high impact. OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself. Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone. This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.

A 2-year randomised, double-blind, placebo-controlled, multicentre study of oral selective iNOS inhibitor, cindunistat (SD-6010), in patients with symptomatic osteoarthritis of the knee
Ann Rheum Dis. 2013 Feb;72(2):187-95. doi: 10.1136/annrheumdis-2012-202239. Epub 2012 Nov 10

Arthroplasty
Perioperative administration of selective cyclooxygenase-2 inhibitors for postoperative pain management in patients after total knee arthroplasty
J Arthroplasty. 2013 Feb;28(2):207-213.e2. doi: 10.1016/j.arth.2012.04.008. Epub 2012 Jun 7